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专利名称：NANOPARTICLES, METHOD FOR
PRODUCING NANOPARTICLES AND USE OFTHE SAME
发明人：MANERO, JAVIER,FILBEY,
JENNIFER,BODERKE, PETER
申请号：EP99911744.3申请日：19990306公开号：EP1061904A1公开日：20001227
摘要：The present invention relates to nanoparticles to have biocompatibility,biodegradable compound polyelectrolyte by polycation and polyanion and bioactivator.The nanoparticle obtains compound polyelectrolyte and at least one crosslinking agentby other processing and has been formed at it. The nanoparticle is prepared the presentinvention also relates to a kind of. Activating agent combines or then the aggregation ofunbonded and aqueous solution acid polymer substance and alkaline matter is
generated with polyelectrolyte with form of nanoparticles, or optionally, it is convertedto form of nanoparticles, this inventive features are that nanoparticle compound
polyelectrolyte is, then at least one crosslinking agent. Nanoparticle of the invention canbe used for applying bioactivator. They have very stable, make the controlled release ofactive agents and do not generate burst effect. Since this method is generated by it,nanoparticle of the invention also only has considerably less remaining organic solvent.
申请人：AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG
地址：65926 Frankfurt am Main DE
国籍：DE
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