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Bacterial packaging strains useful for generation

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专利名称:Bacterial packaging strains useful for

generation and production of recombinantdouble-stranded RNA nucleocapsids anduses thereof

发明人:David Hone,John Fulkerson,Jerald C.

Sadoff,David Onyabe,Michele Stone

申请号:US11284817申请日:20051123

公开号:US20060115493A1公开日:20060601

摘要:Bacterial packaging strains useful for generating recombinant double-strandedRNA nucleocapsids (rdsRNs) are provided. The packaging strains are useful for theproduction of RNA encoding vaccine antigens, bioactive proteins, immunoregulatoryproteins, antisense RNAs, and catalytic RNAs in eukaryotic cells or tissues. RecombinantssRNA is introduced into the strains and packaged to form rdsRNs de novo.

申请人:David Hone,John Fulkerson,Jerald C. Sadoff,David Onyabe,Michele Stone

地址:Rockville MD US,Silver Spring MD US,Washington DC US,Poolesville MDUS,Ellicott City MD US

国籍:US,US,US,US,US

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