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Nanoceria for the treatment of oxidative stress

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专利内容由知识产权出版社提供

专利名称:Nanoceria for the treatment of oxidative

stress

发明人:Kenneth Joseph Reed,Wendi Ann

Costanzo,Joseph Samuel Erlichman,EricLeslie Bell

申请号:US14690781申请日:20150420公开号:US09533007B2公开日:20170103

专利附图:

摘要:A process for making nanoparticles of biocompatible materials is described,

wherein an aqueous reaction mixture comprising cerous ion, citric acid andethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water isprovided along with temperature conditions to directly form, without isolation, a stabledispersion of cerium oxide nanoparticles. These biocompatible cerium oxide

nanoparticles may be used to prevent and/or treat oxidative stress related diseases, suchas stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis,amyotrophic lateral sclerosis, and ischemic reperfusion injury.

申请人:Cerion, LLC

地址:Rochester NY US

国籍:US

代理机构:RatnerPrestia

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