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Transfer of mRNA using polycationic compounds

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专利名称:Transfer of mRNA using polycationic

compounds

发明人:Hoerr, Ingmar, Dr.,Rammensee, Hans-Georg,

Prof. Dr.,Jung, Günther, Prof. Dr.,Obst,Reinhard, Dr.

申请号:EP05022610.9申请日:19990909公开号:EP1619254B1公开日:20101222

摘要:The invention provides a method for the transfer of RNA, especially mRNA, intocells and into organisms. This method is especially suited for applications in the field ofgene therapy. The RNA is transferred in the form of a complex between at least one RNAand at least one cationic, especially polycationic, peptide or protein. Preferablyprotamine, poly-L-lysine and/or histone is used as cationic peptide or protein.

申请人:CUREVAC GMBH

地址:DE

国籍:DE

代理机构:Graf von Stosch, Andreas

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