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专利名称：Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines, a process for theirpreparation and their use as modulators ofneurotransmitter function
发明人：Effland, Richard Charles,Klein, Joseph
Thomas
申请号：EP92116111.3申请日：19920921公开号：EP0534344A1公开日：19930331
摘要：There are disclosed various compounds of the formula below, where n is 1or 2; m is 1 or 2; each X is independently hydrogen or loweralkoxy; Y ishydrogen, halogen or trifluoromethyl; R₁ is hydrogen, loweralkyl, arylloweralkyl,heteroarylloweralkyl, pyridinyl, loweralkylcarbonyl, arylloweralkylcarbonyl,
heteroarylloweralkylcarbonyl, trifluoromethylcarbonyl or arylcarbonyl; and R₂ ishydrogen, loweralkyl, loweralkoxycarbonyl, aminoloweralkylcarbonyl,
loweralkylaminoloweralkylcarbonyl or diloweralkylaminoloweralkylcarbonyl; which areuseful as modulators of neurotransmitter function such as serotonergic and adrenergic,and as such are useful as antidepressants and for the treatment of personality disorderssuch as obsessive compulsive disorders.
申请人：HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED
地址：P.O. Box 2500, Route 202-206 Somerville, NJ 08876-1258 US
国籍：US
代理机构：Losert, Wolfgang Dr.
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