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AZAINDOLE DERIVATIVES WITH A COMBINATION OF PARTIA

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专利名称:AZAINDOLE DERIVATIVES WITH A

COMBINATION OF PARTIAL NICOTINICACETYLCHOLINE RECEPTOR AGONISM ANDDOPAMINE REUPTAKE INHIBITION

发明人:STOIT, Axel,COOLEN, Hein K.A.C.,VAN DER

NEUT, Martina A.W.,KRUSE, Cornelis G.

申请号:EP07787088.9申请日:20070705公开号:EP2041131A1公开日:20090401

摘要:The invention concerns azaindole derivatives having the general formula (I)wherein the symbols have the meanings given in the specification. These compounds havea combination of partial nicotinic acetylcholine receptor agonism and dopamine reuptakeinhibition. The invention also relates to pharmaceutical compositions containing thesecompounds, to methods for preparing them, methods for preparing novel intermediatesuseful for their synthesis, methods for preparing compositions, and uses of suchcompounds and compositions, particularly their use in administering them to patients toachieve a therapeutic effect in disorders in which nicotinic receptors and/or dopaminetransporters are involved, or that can be treated via manipulation of those receptors.

申请人:Solvay Pharmaceuticals B.V.

地址:C.J. van Houtenlaan 36 1381 CP Weesp NL

国籍:NL

代理机构:Tulp, Martinus

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