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专利名称:Methods and compositions useful for
inhibition of alpha v beta 5 mediatedangiogenesis
发明人:Peter Brooks,David A. Cheresh,Martin
Friedlander
申请号:US112906申请日:20051129
公开号:US20060165703A1公开日:20060727
摘要:The present invention describes methods for inhibiting angiogenesis in tissuesusing vitronectin αβantagonists. The αβ-mediated angiogenesis is correlated withexposure to cytokines including vascular endothelial growth factor, transforming growthfactor-α and epidermal growth factor. Inhibition of αβ-mediated angiogenesis isparticularly preferred in vascular endothelial ocular neovascular diseases, in tumorgrowth and in inflammatory conditions, using therapeutic compositions containingαβantagonists.
申请人:Peter Brooks,David A. Cheresh,Martin Friedlander
地址:Carmel NY US,Encinitas CA US,Del Mar CA US
国籍:US,US,US
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