Binding assay using binding agents with tail group

专利名称：Binding assay using binding agents with tail

groups

发明人：Roger Philip Ekins申请号：US11339082申请日：20060125

公开号：US20060204983A1公开日：20060914

摘要：The present invention discloses methods and kits for the determination of theconcentration of one or more analytes in a liquid sample using capture agents

immobilised on a solid support and binding agents for binding the analyte(s), the bindingagents having tail groups capable of binding to the respective capture agent. Preferably,the capture agents and binding agents are complementary oligonucleotides, and thecapture agents are immobilised in the form of microspots. The use of the tail groups andcapture agents can allow the binding of the analyte(s) to the binding agent(s) to takeplace in solution, rather than at a surface, improving the kinetics associated with thisprocess. In addition, the user of the assay can customise any suitable binding agents foruse with a universal support, by attaching tail groups them.

申请人：Roger Philip Ekins

地址：London GB

国籍：GB

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