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4-substituted anthracyclinones and their preparati

来源:九壹网
专利内容由知识产权出版社提供

专利名称:4-substituted anthracyclinones and their

preparation

发明人:Walter Cabri,Silvia De Bernardinis,Franco

Francalanci,Sergio Penco

申请号:US07/646594申请日:19910125公开号:US05218130A公开日:19930608

摘要:4-substituted anthracyclinones of formula (I) ##STR1## wherein R represents ahydrogen atom or a straight or branched alkyl, alkenyl or alkynyl group having from 1 to10 carbon atoms, are intermediates in the preparation of antitumor anthracyclineglycosides of formula (IX): ##STR2## wherein R is as defined above and R.sub.1 is ahydrogen atom or a hydroxy group, and pharmaceutically acceptable salts thereof.

申请人:FARMITALIA CARLO ERBA S R L

代理机构:Oblon, Spivak, McClelland, Maier & Neustadt

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