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RNA molecules

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专利名称:RNA molecules

发明人:SMITH, Neil Andrew,WANG, Ming-Bo,DORAN, Timothy James,TIZARD,Mark,ALLU, Annapurna Devi,GREAVES, IanKevin,GAO, Lingling,ANDERSON, JonathanPaul

申请号:AU2018333285申请日:20180917公开号:AU2018333285A1公开日:20200423

摘要:The present invention relates to new double stranded RNA (dsRNA) structuresand their use in gene silencing. In one embodiment the dsRNA comprises a double hairpin(dumbbell) structure. In another embodiment a proportion of the sense and antisensestrands of the dsRNA molecule contain ribonucleotides that are either basepaired in anon-canonical basepair or are not basepaired.

申请人:Commonwealth Scientific and Industrial Research Organisation

代理人:FB Rice Pty Ltd

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