专利内容由知识产权出版社提供
专利名称：Method of separating components in a
sample using silane-treated silica filtermedia
发明人：Gary L. Gibson,Keith Hayes,Meng H.
Heng,Csilla Kollar,Thomas H. Lane,AnthonyRevis,Landon M. Steele
申请号：US10677404申请日：20031001
公开号：US20040211724A1公开日：20041028
专利附图：
摘要：The present invention provides methods for separating one or more
components of interest from a sample containing particulates and soluble materials. Themethod comprises the steps of: (a) filtering a sample through silica filter media whosesurface silanol groups have reacted with one or more silanes, and (b) simultaneouslycapturing particulates and binding a soluble component to the silica filter media. Thebound soluble component of interest is subsequently eluted from the silica filter media.In one embodiment of the invention, unwanted soluble materials are captured by thetreated silica filter media and desired component of interest is recovered from the flow-through. In another embodiment of the invention, different components of interest arerecovered from both the eluate and the flow-through. Preferred treated silica filtermedia are silane-treated rice hull ash or diatomaceous earth with functional quarternaryammonium group or functional sulphonate group. Particulates suitable for the presentinvention, for example, are microorganisms.
申请人：GIBSON GARY L.,HAYES KEITH,HENG MENG H.,KOLLAR CSILLA,LANE THOMASH.,REVIS ANTHONY,STEELE LANDON M.
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